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Design and Application of Clinical Big Data Management System for Oncology

Ma Lin, Bao Chenlu, Li Qing,Wu Jingyi, Pan Hong’an, Li Pengfei, Zhang Luxia, Zhan Qimin

Strategic Study of CAE 2022, Volume 24, Issue 6,   Pages 127-136 doi: 10.15302/J-SSCAE-2022.06.011

Abstract: Hence, establishing a national clinical big data management system for oncology based on artificialthe quality and efficiency of clinical management for oncology.This study conducted an in-depth analysis of the problems and challenges of clinical data managementtaking the clinical data management for lung cancer in a tertiary hospital as an example.Finally, we proposed some suggestions on the research directions of the clinical big data management&

Keywords： clinical big data     management system     oncology     artificial intelligence     common data model     natural language    

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Basic consideration of research strategies for head and neck cancer

Jin Gao, Ben Panizza, Newell W. Johnson, Scott Coman, Alan R. Clough

Frontiers of Medicine 2012, Volume 6, Issue 4,   Pages 339-353 doi: 10.1007/s11684-012-0213-7

Abstract: of aetiology, key risk factors related to the development of head and neck cancer, basic features of clinicalresearch strategies on the basis of current knowledge, which should ultimately lead to the improvement of clinicalmanagement.

Keywords： clinical management     head and neck cancer     prevention and early detection     research strategies     risk factors    

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Ontological reconstruction of the clinical terminology of traditional Chinese medicine

Li Ma,Baoyan Liu,Qi Xie,Shusong Mao,Zhiwei Cui

Frontiers of Medicine 2014, Volume 8, Issue 3,   Pages 358-361 doi: 10.1007/s11684-014-0348-9

Abstract:

This study proposes the ontological reconstruction of the current clinical terminology of traditionalof preliminary work related to the said reconstruction, including the ontology-based analysis of TCM clinicalWe conclude that the ontological reconstruction of TCM clinical terminology provides a proper translation

Keywords： ontology     traditional Chinese medicine     clinical terminology    

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Design and implementation of a platform for configuring clinical dynamic safety checklist applications None

Shan NAN, Xu-dong LU, Pieter VAN GORP, Hendrikus H. M. KORSTEN, Richard VDOVJAK, Uzay KAYMAK, Hui-long DUAN

Frontiers of Information Technology & Electronic Engineering 2018, Volume 19, Issue 7,   Pages 937-946 doi: 10.1631/FITEE.1700623

Abstract: community propose to implement checklists in dynamic checklist applications that can be integrated into the clinicalWe define a number of design criteria regarding point of care and clinical processes by analyzing theThen, by applying rule-based clinical decision support and workflow management technologies, we designFinally, we build a platform in various design cycle iterations, driven by multiple clinical cases.

Keywords： Checklist     Workflow     Clinical decision support     Process management     Patient safety    

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The clinical impact of tricuspid regurgitation in patients with a biatrial orthotopic heart transplant

Frontiers of Medicine 2023, Volume 17, Issue 3,   Pages 527-533 doi: 10.1007/s11684-022-0967-5

Abstract: In this study, we aim to elucidate the clinical impact and long-term course of tricuspid regurgitation

Keywords： orthotopic heart transplant     tricuspid regurgitation     clinical impact     biatrial heart transplantation    

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Obesity-related glomerulopathy: pathogenesis, pathologic, clinical characteristics and treatment

Tianhua Xu, Zitong Sheng, Li Yao

Frontiers of Medicine 2017, Volume 11, Issue 3,   Pages 340-348 doi: 10.1007/s11684-017-0570-3

Abstract: A slow increase of subnephrotic proteinuria (<3.5 g/d) is the most common clinical manifestation of

Keywords： obesity-related glomerulopathy     pathogenesis     pathologic     clinical characteristics    

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Coronavirus disease 2019 (COVID-19): a clinical update

Min Zhou, Xinxin Zhang, Jieming Qu

Frontiers of Medicine 2020, Volume 14, Issue 2,   Pages 126-135 doi: 10.1007/s11684-020-0767-8

Abstract: promising antivirals, convalescent plasma transfusion, and tocilizumab needs to be investigated by ongoing clinical

Keywords： coronavirus disease 2019     epidemiology     pathology     radiology     clinical characteristics     treatment    

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Hypertension in patients with CKD in China: clinical characteristics and management

Guangyan Cai, Xiangmei Chen

Frontiers of Medicine 2017, Volume 11, Issue 3,   Pages 307-309 doi: 10.1007/s11684-017-0578-8

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Bone metastasis of hepatocellular carcinoma: facts and hopes from clinical and translational perspectives

Frontiers of Medicine 2022, Volume 16, Issue 4,   Pages 551-573 doi: 10.1007/s11684-022-0928-z

Abstract: To date, no consensus or guidelines have been reached or formulated for the prevention and management

Keywords： HCC     bone     osteotropism     clinical     basic researches     advances    

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Heterogeneity of the tumor immune microenvironment and clinical interventions

Frontiers of Medicine 2023, Volume 17, Issue 4,   Pages 617-648 doi: 10.1007/s11684-023-1015-9

Abstract: Heterogeneity of the tumor immune microenvironment and clinical interventions

Keywords： Heterogeneity tumor immune    

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Pathogen evolution, prevention/control strategy and clinical features of COVID-19: experiences from China

Frontiers of Medicine doi: 10.1007/s11684-023-1043-5

Abstract: The overall clinical features of variants of concern (VOC), heterogeneity in the clinical manifestations

Keywords： coronavirus disease 2019     SARS-CoV-2     epidemiology     clinical features    

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The Current Situation and Development of Health Management in China

Li Jiang,Tao Sha,Li Ming,Fu Hua,Wang Ke’an,Tian Chuansheng and Wang Longde

Strategic Study of CAE 2017, Volume 19, Issue 2,   Pages 8-15 doi: 10.15302/J-SSCAE-2017.02.002

Abstract: The results of this study indicate that China has some problems in current health management, for exampleservices; foreign-funded enterprises and large state-owned enterprises have carried out health management, but small- and medium-sized enterprises in China lack the independent ability to carry out health managementis often provided for high-end customers as an additional option; and health management service companiesdo not provide real health management services, but only physical examinations.

Keywords： health management     health risk appraisal     life span     basic public health service     clinical preventive    

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Genetic and clinical markers for predicting treatment responsiveness in rheumatoid arthritis

Xin Wu, Xiaobao Sheng, Rong Sheng, Hongjuan Lu, Huji Xu

Frontiers of Medicine 2019, Volume 13, Issue 4,   Pages 411-419 doi: 10.1007/s11684-018-0659-3

Abstract: These predictors include but are certainly not limited to genetic variations, clinical factors, and demographicHowever, no clinical application is currently available.

Keywords： rheumatoid arthritis     gene     clinical markers     therapy    

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Biological properties and clinical applications of berberine

Danyang Song, Jianyu Hao, Daiming Fan

Frontiers of Medicine 2020, Volume 14, Issue 5,   Pages 564-582 doi: 10.1007/s11684-019-0724-6

Abstract: Berberine, an isoquinoline alkaloid isolated from the Chinese herb and other plants, has a wide range of pharmacological properties. Berberine can be used to treat many diseases, such as cancer and digestive, metabolic, cardiovascular, and neurological diseases. Berberine has protective capacities in digestive diseases. It can inhibit toxins and bacteria, including , protect the intestinal epithelial barrier from injury, and ameliorate liver injury. Berberine also inhibits the proliferation of various types of cancer cells and impedes invasion and metastasis. Recent evidence has confirmed that berberine improves the efficacy and safety of chemoradiotherapies. In addition, berberine regulates glycometabolism and lipid metabolism, improves energy expenditure, reduces body weight, and alleviates nonalcoholic fatty liver disease. Berberine also improves cardiovascular hemodynamics, suppresses ischemic arrhythmias, attenuates the development of atherosclerosis, and reduces hypertension. Berberine shows potent neuroprotective effects, including antioxidative, antiapoptotic, and anti-ischemic. Furthermore, berberine exerts protective effects against other diseases. The mechanisms of its functions have been extensively explored, but much remains to be clarified. This article summarizes the main pharmacological actions of berberine and its mechanisms in cancer and digestive, metabolic, cardiovascular, and neurological diseases.

Keywords： berberine     Coptis chinensis     pharmacological properties     mechanism     clinical applications    

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Anatomy and embryology of umbilicus in newborns: a review and clinical correlations

Abdelmonem A. Hegazy

Frontiers of Medicine 2016, Volume 10, Issue 3,   Pages 271-277 doi: 10.1007/s11684-016-0457-8

Abstract: This article aimed to address the basic knowledge of the umbilicus in relation to clinical disordersThus, the umbilicus is prone to various clinical disorders.

Keywords： anatomy     embryology     newborns     umbilicus    

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Title Author Date Type Operation

Design and Application of Clinical Big Data Management System for Oncology

Ma Lin, Bao Chenlu, Li Qing,Wu Jingyi, Pan Hong’an, Li Pengfei, Zhang Luxia, Zhan Qimin

Journal Article

Basic consideration of research strategies for head and neck cancer

Jin Gao, Ben Panizza, Newell W. Johnson, Scott Coman, Alan R. Clough

Journal Article

Ontological reconstruction of the clinical terminology of traditional Chinese medicine

Li Ma,Baoyan Liu,Qi Xie,Shusong Mao,Zhiwei Cui

Journal Article

Design and implementation of a platform for configuring clinical dynamic safety checklist applications

Shan NAN, Xu-dong LU, Pieter VAN GORP, Hendrikus H. M. KORSTEN, Richard VDOVJAK, Uzay KAYMAK, Hui-long DUAN

Journal Article

The clinical impact of tricuspid regurgitation in patients with a biatrial orthotopic heart transplant

Journal Article

Obesity-related glomerulopathy: pathogenesis, pathologic, clinical characteristics and treatment

Tianhua Xu, Zitong Sheng, Li Yao

Journal Article

Coronavirus disease 2019 (COVID-19): a clinical update

Min Zhou, Xinxin Zhang, Jieming Qu

Journal Article

Hypertension in patients with CKD in China: clinical characteristics and management

Guangyan Cai, Xiangmei Chen

Journal Article

Bone metastasis of hepatocellular carcinoma: facts and hopes from clinical and translational perspectives

Journal Article

Heterogeneity of the tumor immune microenvironment and clinical interventions

Journal Article

Pathogen evolution, prevention/control strategy and clinical features of COVID-19: experiences from China

Journal Article

The Current Situation and Development of Health Management in China

Li Jiang,Tao Sha,Li Ming,Fu Hua,Wang Ke’an,Tian Chuansheng and Wang Longde

Journal Article

Genetic and clinical markers for predicting treatment responsiveness in rheumatoid arthritis

Xin Wu, Xiaobao Sheng, Rong Sheng, Hongjuan Lu, Huji Xu

Journal Article

Biological properties and clinical applications of berberine

Danyang Song, Jianyu Hao, Daiming Fan

Journal Article

Anatomy and embryology of umbilicus in newborns: a review and clinical correlations

Abdelmonem A. Hegazy

Journal Article